Birth Defect

Teratogen Update: Environmentally Induced Birth Defect Risks

Our society's expectations of perfect babies, coupled with a belief that someone should be held responsible for birth defects, makes legal action on behalf of congenitally malformed infants common. In some instances the alleged cause of the malformation is exposure to drugs, industrial chemicals, radiation, or infectious agents. A convenient source of pertinent information on the etiology, path...

Disrupted Intercellular Communication Causes a Disfiguring Birth Defect

-Glial fibrillary acidic protein (GFA) was assayed in nerve-tumour extracts and located in these tumours by indirect immunofluorescence study. We conclude that GFA is a specific marker of both malignant and normal astrocytes. Non-astrocytic tumours (oligodendroglioma, meningioma) do not contain GFA. Tumours with astrocytic differentiation potential (medulloblastoma) may contain GFA. Comparison ...

[Reliability of birth defect data on birth certificates of Rio de Janeiro, Brazil, 2004].

This study assessed the reliability of birth certificate data related to birth defects in Brazil's Live Birth Information System (SINASC). We selected 24 maternity hospitals in the Unified National Health System (SUS) and compared the reports of birth defects from birth certificates with medical records of mothers and live born infants in the city of Rio de Janeiro for the year 2004. After tran...

Circulatory adjustments after birth: effects on ventricular septal defect.

The haemodynamic effects and clinical manifestations of congenital heart lesions may be greatly influenced by developmental changes in the circulation. The sequential changes associated with abnormal communications between the systemic and pulmonary circulations are well typified by the effect on ventricular septal defect. The possible influences of ventricular septal defect on the foetal circu...

Introduction: birth defect surveillance in the United States.